Discovery of T-Cell Infection and Apoptosis by Middle East Respiratory Syndrome Coronavirus

Por Ying, Tianlei, Li, Wei, Dimitrov, Dimiter S.
Publicado no J Infect Dis (2016)

Bispecific Engineered Antibody Domains (Nanoantibodies) That Interact Noncompetitively with an HIV-1 Neutralizing Epitope and FcRn

Por Gong, Rui, Wang, Yanping, Ying, Tianlei, Dimitrov, Dimiter S.
Publicado em 2012

Urgent development of effective therapeutic and prophylactic agents to control the emerging threat of Middle East respiratory syndrome (MERS)

Por Lu, Lu, Xia, Shuai, Ying, Tianlei, Jiang, Shibo
Publicado no Emerg Microbes Infect (2015)

Soluble Monomeric IgG1 Fc

Por Ying, Tianlei, Chen, Weizao, Gong, Rui, Feng, Yang, Dimitrov, Dimiter S.
Publicado em 2012

Development of human neutralizing monoclonal antibodies for prevention and therapy of MERS-CoV infections

Por Ying, Tianlei, Li, Haoyang, Lu, Lu, Dimitrov, Dimiter S., Jiang, Shibo
Publicado no Microbes Infect (2015)

Monomeric IgG1 Fc molecules displaying unique Fc receptor interactions that are exploitable to treat inflammation-mediated diseases

Por Ying, Tianlei, Feng, Yang, Wang, Yanping, Chen, Weizao, Dimitrov, Dimiter S.
Publicado no MAbs (2014)

Interactions of IgG1 CH2 and CH3 Domains with FcRn

Por Ying, Tianlei, Ju, Tina W., Wang, Yanping, Prabakaran, Ponraj, Dimitrov, Dimiter S.
Publicado em 2014

Engineered Fc based antibody domains and fragments as novel scaffolds

Por Ying, Tianlei, Gong, Rui, Ju, Tina W., Prabakaran, Ponraj, Dimitrov, Dimiter S.
Publicado em 2014

Engineered Soluble Monomeric IgG1 CH3 Domain: GENERATION, MECHANISMS OF FUNCTION, AND IMPLICATIONS FOR DESIGN OF BIOLOGICAL THERAPEUTICS

Por Ying, Tianlei, Chen, Weizao, Feng, Yang, Wang, Yanping, Gong, Rui, Dimitrov, Dimiter S.
Publicado em 2013

Germlining of the HIV-1 broadly neutralizing antibody domain m36

Por Chen, Weizao, Li, Wei, Ying, Tianlei, Wang, Yanping, Feng, Yang, Dimitrov, Dimiter S.
Publicado no Antiviral Res (2015)

N-Terminal Truncation of an Isolated Human IgG1 CH2 Domain Significantly Increases its Stability and Aggregation Resistance

Por Gong, Rui, Wang, Yanping, Ying, Tianlei, Feng, Yang, Streaker, Emily, Prabakaran, Ponraj, Dimitrov, Dimiter S.
Publicado em 2013

No evidence for a superior platform to develop therapeutic antibodies rapidly in response to MERS-CoV and other emerging viruses

Por Dimitrov, Dimiter S., Jiang, Shibo, Ying, Tianlei, Tseng, Chien-Te K., Zhang, Linqi, Yuen, Kwok-yung
Publicado no Proc Natl Acad Sci U S A (2015)

Engineered antibody domains with significantly increased transcytosis and half-life in macaques mediated by FcRn

Por Ying, Tianlei, Wang, Yanping, Feng, Yang, Prabakaran, Ponraj, Gong, Rui, Wang, Lili, Crowder, Karalyne, Dimitrov, Dimiter S
Publicado no MAbs (2015)

Structural Basis for Cytochrome c Y67H Mutant to Function as a Peroxidase

Por Lan, Wenxian, Wang, Zhonghua, Yang, Zhongzheng, Ying, Tianlei, Zhang, Xu, Tan, Xiangshi, Liu, Maili, Cao, Chunyang, Huang, Zhong-Xian
Publicado em 2014

Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody

Por Ying, Tianlei, Prabakaran, Ponraj, Du, Lanying, Shi, Wei, Feng, Yang, Wang, Yanping, Wang, Lingshu, Li, Wei, Jiang, Shibo, Dimitrov, Dimiter S., Zhou, Tongqing
Publicado no Nat Commun (2015)

An immunogen containing four tandem 10E8 epitope repeats with exposed key residues induces antibodies that neutralize HIV-1 and activates an ADCC reporter gene

Por Sun, Zhiwu, Zhu, Yun, Wang, Qian, Ye, Ling, Dai, Yanyan, Su, Shan, Yu, Fei, Ying, Tianlei, Yang, Chinglai, Jiang, Shibo, Lu, Lu
Publicado no Emerg Microbes Infect (2016)

Exceptionally Potent and Broadly Cross-Reactive, Bispecific Multivalent HIV-1 Inhibitors Based on Single Human CD4 and Antibody Domains

Por Chen, Weizao, Feng, Yang, Prabakaran, Ponraj, Ying, Tianlei, Wang, Yanping, Sun, Jianping, Macedo, Camila D. S., Zhu, Zhongyu, He, Yuxian, Polonis, Victoria R., Dimitrov, Dimiter S.
Publicado em 2014

Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)–Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV Infection

Por Houser, Katherine V., Gretebeck, Lisa, Ying, Tianlei, Wang, Yanping, Vogel, Leatrice, Lamirande, Elaine W., Bock, Kevin W., Moore, Ian N., Dimitrov, Dimiter S., Subbarao, Kanta
Publicado no J Infect Dis (2016)

Conformational Toggling of Yeast Iso-1-Cytochrome c in the Oxidized and Reduced States

Por Lan, Wenxian, Wang, Zhonghua, Yang, Zhongzheng, Zhu, Jing, Ying, Tianlei, Jiang, Xianwang, Zhang, Xu, Wu, Houming, Liu, Maili, Tan, Xiangshi, Cao, Chunyang, Huang, Zhong-Xian
Publicado em 2011

Improving the CH1-CK heterodimerization and pharmacokinetics of 4Dm2m, a novel potent CD4-antibody fusion protein against HIV-1

Por Chen, Weizao, Bardhi, Ariola, Feng, Yang, Wang, Yanping, Qi, Qianqian, Li, Wei, Zhu, Zhongyu, Dyba, Marzena A., Ying, Tianlei, Jiang, Shibo, Goldstein, Harris, Dimitrov, Dimiter S.
Publicado no MAbs (2016)