A carregar...
Engineered antibody domains with significantly increased transcytosis and half-life in macaques mediated by FcRn
Engineered antibody domains (eAds) are promising candidate therapeutics but their half-life is relatively short partly due to weak or absent binding to the neonatal Fc receptor (FcRn). We developed a novel approach to increase the eAd binding to FcRn based on a combination of structure-based design,...
Na minha lista:
| Publicado no: | MAbs |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622838/ https://ncbi.nlm.nih.gov/pubmed/26179052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1067353 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|