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Germlining of the HIV-1 broadly neutralizing antibody domain m36

Engineered antibody domains (eAds) have emerged as a novel class of HIV-1 inhibitors and are currently under preclinical testing as promising drug candidates for prevention and therapy of HIV-1 infection. Reverse mutation of antibodies to germline sequences (germlining) could not only identify less...

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Bibliografiske detaljer
Udgivet i:Antiviral Res
Main Authors: Chen, Weizao, Li, Wei, Ying, Tianlei, Wang, Yanping, Feng, Yang, Dimitrov, Dimiter S.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357557/
https://ncbi.nlm.nih.gov/pubmed/25676867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2015.02.001
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