Computational modelling for the sustainable management of chemicals

по Worth, Andrew P.
Опубликовано в: Comput Toxicol (2020)

Canine Degenerative Lumbosacral Stenosis: Prevalence, Impact And Management Strategies

по Worth, Andrew, Meij, Björn, Jeffery, Nicholas
Опубликовано в: Vet Med (Auckl) (2019)

Dedication to Dr J.M. Zaldívar Comenges (1958–2012)

по Whelan, Maurice, Worth, Andrew, Coecke, Sandra, Blaauboer, Bas
Опубликовано в: Toxicol In Vitro (2017)

Carcinogenicity assessment: Addressing the challenges of cancer and chemicals in the environment

по Madia, Federica, Worth, Andrew, Whelan, Maurice, Corvi, Raffaella
Опубликовано в: Environ Int (2019)

Optimising testing strategies for classification of human health and environmental hazards – A proof-of-concept study

по Da Silva, Emilie, Baun, Anders, Berggren, Elisabet, Worth, Andrew
Опубликовано в: Toxicol Lett (2020)

The role of validation in establishing the scientific credibility of predictive toxicology approaches intended for regulatory application

по Patterson, Eann A., Whelan, Maurice P., Worth, Andrew P.
Опубликовано в: Comput Toxicol (2021)

Gaining acceptance in next generation PBK modelling approaches for regulatory assessments – An OECD international effort

по Paini, Alicia, Tan, Yu-Mei, Sachana, Magdalini, Worth, Andrew
Опубликовано в: Comput Toxicol (2021)

The margin of internal exposure (MOIE) concept for dermal risk assessment based on oral toxicity data – A case study with caffeine

по Bessems, Jos G.M., Paini, Alicia, Gajewska, Monika, Worth, Andrew
Опубликовано в: Toxicology (2017)

Application of new statistical distribution approaches for environmental mixture risk assessment: A case study

по Kienzler, Aude, Bopp, Stephanie, Halder, Marlies, Embry, Michelle, Worth, Andrew
Опубликовано в: Sci Total Environ (2019)

Assessment of the predictive capacity of a physiologically based kinetic model using a read-across approach

по Paini, Alicia, Worth, Andrew, Kulkarni, Sunil, Ebbrell, David, Madden, Judith
Опубликовано в: Comput Toxicol (2021)

Integration of data across toxicity endpoints for improved safety assessment of chemicals: the example of carcinogenicity assessment

по Madia, Federica, Pillo, Gelsomina, Worth, Andrew, Corvi, Raffaella, Prieto, Pilar
Опубликовано в: Arch Toxicol (2021)

From in vitro to in vivo: Integration of the virtual cell based assay with physiologically based kinetic modelling

по Paini, Alicia, Sala Benito, Jose Vicente, Bessems, Jos, Worth, Andrew P.
Опубликовано в: Toxicol In Vitro (2017)

Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications

по Paini, Alicia, Leonard, Jeremy A., Kliment, Tomas, Tan, Yu-Mei, Worth, Andrew
Опубликовано в: Regul Toxicol Pharmacol (2017)

Unlocking the potential of in silico chemical safety assessment – A report on a cross-sector symposium on current opportunities and future challenges

по Cronin, Mark T.D., Madden, Judith C., Yang, Chihae, Worth, Andrew P.
Опубликовано в: Comput Toxicol (2019)

Role of Physiologically Based Kinetic modelling in addressing environmental chemical mixtures – A review

по Desalegn, Anteneh, Bopp, Stephanie, Asturiol, David, Lamon, Lara, Worth, Andrew, Paini, Alicia
Опубликовано в: Comput Toxicol (2019)

Untargeted Metabolomics from Biological Sources Using Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry (UPLC-HRMS)

по Snyder, Nathaniel W., Khezam, Maya, Mesaros, Clementina A., Worth, Andrew, Blair, Ian A.
Опубликовано 2013

Inhibition of Neuronal Cell Mitochondrial Complex I with Rotenone Increases Lipid β-Oxidation, Supporting Acetyl-Coenzyme A Levels

по Worth, Andrew J., Basu, Sankha S., Snyder, Nathaniel W., Mesaros, Clementina, Blair, Ian A.
Опубликовано 2014

Metabolism of propionic acid to a novel acyl-coenzyme A thioester by mammalian cell lines and platelets

по Snyder, Nathaniel W., Basu, Sankha S., Worth, Andrew J., Mesaros, Clementina, Blair, Ian A.
Опубликовано в: J Lipid Res (2015)

Stable isotope dilution liquid chromatography-mass spectrometry analysis of cellular and tissue medium- and long-chain acyl-coenzyme A thioesters

по Snyder, Nathaniel W., Basu, Sankha S., Zhou, Zinan, Worth, Andrew J., Blair, Ian A.
Опубликовано в: Rapid Commun Mass Spectrom (2014)

Virtual Cell Based Assay simulations of intra-mitochondrial concentrations in hepatocytes and cardiomyocytes

по Worth, Andrew P., Louisse, Jochem, Macko, Peter, Sala Benito, J.V., Paini, Alicia
Опубликовано в: Toxicol In Vitro (2017)