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From in vitro to in vivo: Integration of the virtual cell based assay with physiologically based kinetic modelling
Physiologically based kinetic (PBK) models and the virtual cell based assay can be linked to form so called physiologically based dynamic (PBD) models. This study illustrates the development and application of a PBK model for prediction of estragole-induced DNA adduct formation and hepatotoxicity in...
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| Publicado no: | Toxicol In Vitro |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Pergamon Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5742636/ https://ncbi.nlm.nih.gov/pubmed/28663056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2017.06.015 |
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