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From in vitro to in vivo: Integration of the virtual cell based assay with physiologically based kinetic modelling

Physiologically based kinetic (PBK) models and the virtual cell based assay can be linked to form so called physiologically based dynamic (PBD) models. This study illustrates the development and application of a PBK model for prediction of estragole-induced DNA adduct formation and hepatotoxicity in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Toxicol In Vitro
Egile Nagusiak: Paini, Alicia, Sala Benito, Jose Vicente, Bessems, Jos, Worth, Andrew P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Pergamon Press 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742636/
https://ncbi.nlm.nih.gov/pubmed/28663056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2017.06.015
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