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Gaining acceptance in next generation PBK modelling approaches for regulatory assessments – An OECD international effort

Physiologically Based Kinetic (PBK) models are valuable tools to help define safe external levels of chemicals based on internal doses at target organs in experimental animals, humans and organisms used in environmental risk assessment. As the toxicity testing paradigm shifts to alternative testing...

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Detalhes bibliográficos
Publicado no:Comput Toxicol
Main Authors: Paini, Alicia, Tan, Yu-Mei, Sachana, Magdalini, Worth, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130668/
https://ncbi.nlm.nih.gov/pubmed/34027244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.comtox.2021.100163
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