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Gaining acceptance in next generation PBK modelling approaches for regulatory assessments – An OECD international effort

Physiologically Based Kinetic (PBK) models are valuable tools to help define safe external levels of chemicals based on internal doses at target organs in experimental animals, humans and organisms used in environmental risk assessment. As the toxicity testing paradigm shifts to alternative testing...

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Bibliografiske detaljer
Udgivet i:Comput Toxicol
Main Authors: Paini, Alicia, Tan, Yu-Mei, Sachana, Magdalini, Worth, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier B.V 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130668/
https://ncbi.nlm.nih.gov/pubmed/34027244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.comtox.2021.100163
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