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Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications

Physiologically based kinetic (PBK) models are used widely throughout a number of working sectors, including academia and industry, to provide insight into the dosimetry related to observed adverse health effects in humans and other species. Use of these models has increased over the last several de...

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Detalhes bibliográficos
Publicado no:Regul Toxicol Pharmacol
Main Authors: Paini, Alicia, Leonard, Jeremy A., Kliment, Tomas, Tan, Yu-Mei, Worth, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656087/
https://ncbi.nlm.nih.gov/pubmed/28866268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yrtph.2017.08.019
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