Untangling the Web: Toxic and Protective Effects of Neuroinflammation and PGE(2) Signaling in Alzheimer’s Disease

Por Woodling, Nathaniel S., Andreasson, Katrin I.
Publicado no ACS Chem Neurosci (2016)

Shifting equilibriums in Alzheimer’s disease: the complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis

Por Gray, Sophie C., Kinghorn, Kerri J., Woodling, Nathaniel S.
Publicado no Neural Regen Res (2020)

Inflammatory Cyclooxygenase Activity and PGE(2) Signaling in Models of Alzheimer’s Disease

Por Johansson, Jenny U., Woodling, Nathaniel S., Shi, Ju, Andreasson, Katrin I.
Publicado no Curr Immunol Rev (2015)

Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling

Por Woodling, Nathaniel S., Rajasingam, Arjunan, Minkley, Lucy J., Rizzo, Alberto, Partridge, Linda
Publicado no BMC Biol (2020)

The prostaglandin E(2) EP4 receptor exerts anti-inflammatory effects in brain innate immunity

Por Shi, Ju, Johansson, Jenny, Woodling, Nathaniel S., Wang, Qian, Montine, Thomas J., Andreasson, Katrin
Publicado em 2010

Microarray analysis of the in vivo response of microglia to Aβ peptides in mice with conditional deletion of the prostaglandin EP2 receptor

Por Johansson, Jenny U., Woodling, Nathaniel S., Brown, Holden D., Wang, Qian, Andreasson, Katrin I.
Publicado no Genom Data (2015)

PICALM rescues glutamatergic neurotransmission, behavioural function and survival in a Drosophila model of Aβ42 toxicity

Por Yu, Yifan, Niccoli, Teresa, Ren, Ziyu, Woodling, Nathaniel S, Aleyakpo, Benjamin, Szabadkai, Gyorgy, Partridge, Linda
Publicado no Hum Mol Genet (2020)

Deficiency in Neuronal TGF-β Signaling Leads to Nigrostriatal Degeneration and Activation of TGF-β Signaling Protects against MPTP Neurotoxicity in Mice

Por Tesseur, Ina, Nguyen, Andy, Chang, Betty, Li, Lulin, Woodling, Nathaniel S., Wyss-Coray, Tony, Luo, Jian
Publicado no J Neurosci (2017)

Signaling via the prostaglandin E(2) receptor EP4 exerts neuronal and vascular protection in a mouse model of cerebral ischemia

Por Liang, Xibin, Lin, Lu, Woodling, Nathaniel S., Wang, Qian, Anacker, Christoph, Pan, Tingting, Merchant, Milton, Andreasson, Katrin
Publicado em 2011

Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E(2) EP4 Receptor Signaling

Por Woodling, Nathaniel S., Wang, Qian, Priyam, Prachi G., Larkin, Paul, Shi, Ju, Johansson, Jenny U., Zagol-Ikapitte, Irene, Boutaud, Olivier, Andreasson, Katrin I.
Publicado em 2014

Prostaglandin signaling suppresses beneficial microglial function in Alzheimer’s disease models

Por Johansson, Jenny U., Woodling, Nathaniel S., Wang, Qian, Panchal, Maharshi, Liang, Xibin, Trueba-Saiz, Angel, Brown, Holden D., Mhatre, Siddhita D., Loui, Taylor, Andreasson, Katrin I.
Publicado no J Clin Invest (2014)

A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin

Por Kinghorn, Kerri J., Grönke, Sebastian, Castillo-Quan, Jorge Iván, Woodling, Nathaniel S., Li, Li, Sirka, Ernestas, Gegg, Matthew, Mills, Kevin, Hardy, John, Bjedov, Ivana, Partridge, Linda
Publicado no J Neurosci (2016)

Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system

Por Bolukbasi, Ekin, Woodling, Nathaniel S., Ivanov, Dobril K., Adcott, Jennifer, Foley, Andrea, Rajasingam, Arjunan, Gittings, Lauren M., Aleyakpo, Benjamin, Niccoli, Teresa, Thornton, Janet M., Partridge, Linda
Publicado no Proc Natl Acad Sci U S A (2021)

Inflammatory prostaglandin E(2) signaling in a mouse model of Alzheimer’s disease

Por Shi, Ju, Wang, Qian, Johansson, Jenny U., Liang, Xibin, Woodling, Nathaniel S., Priyam, Prachi, Loui, Taylor M., Merchant, Milton, Breyer, Richard M., Montine, Thomas J., Andreasson, Katrin
Publicado em 2012

The neuronal receptor tyrosine kinase Alk is a target for longevity

Por Woodling, Nathaniel S., Aleyakpo, Benjamin, Dyson, Miranda Claire, Minkley, Lucy J., Rajasingam, Arjunan, Dobson, Adam J., Leung, Kristie H. C., Pomposova, Simona, Fuentealba, Matías, Alic, Nazif, Partridge, Linda
Publicado no Aging Cell (2020)

Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold

Por Hof Patrick R, Andreasson Katrin I, Woodling Nathaniel S, Schoen Michael, Arons Magali, Udvardi Patrick T, Schmeisser Michael J, Grabrucker Andreas M, Buxbaum Joseph D, Garner Craig C, Boeckers Tobias M
Publicado em 2011-09-01

Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold

Por Grabrucker, Andreas M, Schmeisser, Michael J, Udvardi, Patrick T, Arons, Magali, Schoen, Michael, Woodling, Nathaniel S, Andreasson, Katrin I, Hof, Patrick R, Buxbaum, Joseph D, Garner, Craig C, Boeckers, Tobias M
Publicado em 2011

Suppression of Inflammation with Conditional Deletion of the Prostaglandin E(2) EP2 Receptor in Macrophages and Brain Microglia

Por Johansson, Jenny U., Pradhan, Suraj, Lokteva, Ludmila A., Woodling, Nathaniel S., Ko, Novie, Brown, Holden D., Wang, Qian, Loh, Christina, Cekanaviciute, Egle, Buckwalter, Marion, Manning-Boğ, Amy B., Andreasson, Katrin I.
Publicado em 2013

Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila

Por Bjedov, Ivana, Cochemé, Helena M., Foley, Andrea, Wieser, Daniela, Woodling, Nathaniel S., Castillo-Quan, Jorge Iván, Norvaisas, Povilas, Lujan, Celia, Regan, Jennifer C., Toivonen, Janne M., Murphy, Michael P., Thornton, Janet, Kinghorn, Kerri J., Neufeld, Thomas P., Cabreiro, Filipe, Partridge, Linda
Publicado no PLoS Genet (2020)

Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer’s disease model mice

Por Woodling, Nathaniel S., Colas, Damien, Wang, Qian, Minhas, Paras, Panchal, Maharshi, Liang, Xibin, Mhatre, Siddhita D., Brown, Holden, Ko, Novie, Zagol-Ikapitte, Irene, van der Hart, Marieke, Khroyan, Taline V., Chuluun, Bayarsaikhan, Priyam, Prachi G., Milne, Ginger L., Rassoulpour, Arash, Boutaud, Olivier, Manning-Boğ, Amy B., Heller, H. Craig, Andreasson, Katrin I.
Publicado no Brain (2016)