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Inflammatory Cyclooxygenase Activity and PGE(2) Signaling in Models of Alzheimer’s Disease

The inflammatory response is a fundamental driving force in the pathogenesis of Alzheimer’s disease (AD). In the setting of accumulating immunogenic Aß peptide assemblies, microglia, the innate immune cells of the brain, generate a non-resolving immune response and fail to adequately clear accumulat...

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Detalhes bibliográficos
Publicado no:Curr Immunol Rev
Main Authors: Johansson, Jenny U., Woodling, Nathaniel S., Shi, Ju, Andreasson, Katrin I.
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384338/
https://ncbi.nlm.nih.gov/pubmed/28413375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1573395511666150707181414
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