Parkin’ control: regulation of PGC-1α through PARIS in Parkinson’s disease

gan Castillo-Quan, Jorge Iván
Cyhoeddwyd 2011

From white to brown fat through the PGC-1α-dependent myokine irisin: implications for diabetes and obesity

gan Castillo-Quan, Jorge Iván
Cyhoeddwyd 2012

Mitochondrial dysfunction and defects in lipid homeostasis as therapeutic targets in neurodegeneration with brain iron accumulation

gan Kinghorn, Kerri J., Castillo-Quan, Jorge Iván
Cyhoeddwyd yn Rare Dis (2016)

Untangling longevity, dauer, and healthspan in Caenorhabditis elegans insulin/IGF-1-signalling

gan Ewald, Collin Yvès, Castillo-Quan, Jorge Iván, Blackwell, T. Keith
Cyhoeddwyd yn Gerontology (2017)

The emerging role of autophagic-lysosomal dysfunction in Gaucher disease and Parkinson's disease

gan Kinghorn, Kerri J., Asghari, Amir M., Castillo-Quan, Jorge Iván
Cyhoeddwyd yn Neural Regen Res (2017)

A triple drug combination targeting components of the nutrient-sensing network maximizes longevity

gan Castillo-Quan, Jorge Iván, Tain, Luke S., Kinghorn, Kerri J., Li, Li, Grönke, Sebastian, Hinze, Yvonne, Blackwell, T. Keith, Bjedov, Ivana, Partridge, Linda
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2019)

A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin

gan Kinghorn, Kerri J., Grönke, Sebastian, Castillo-Quan, Jorge Iván, Woodling, Nathaniel S., Li, Li, Sirka, Ernestas, Gegg, Matthew, Mills, Kevin, Hardy, John, Bjedov, Ivana, Partridge, Linda
Cyhoeddwyd yn J Neurosci (2016)

Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis

gan Castillo-Quan, Jorge Iván, Li, Li, Kinghorn, Kerri J., Ivanov, Dobril K., Tain, Luke S., Slack, Cathy, Kerr, Fiona, Nespital, Tobias, Thornton, Janet, Hardy, John, Bjedov, Ivana, Partridge, Linda
Cyhoeddwyd yn Cell Rep (2016)

Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction

gan Kinghorn, Kerri J., Castillo-Quan, Jorge Iván, Bartolome, Fernando, Angelova, Plamena R., Li, Li, Pope, Simon, Cochemé, Helena M., Khan, Shabana, Asghari, Shabnam, Bhatia, Kailash P., Hardy, John, Abramov, Andrey Y., Partridge, Linda
Cyhoeddwyd yn Brain (2015)

Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila

gan Bjedov, Ivana, Cochemé, Helena M., Foley, Andrea, Wieser, Daniela, Woodling, Nathaniel S., Castillo-Quan, Jorge Iván, Norvaisas, Povilas, Lujan, Celia, Regan, Jennifer C., Toivonen, Janne M., Murphy, Michael P., Thornton, Janet, Kinghorn, Kerri J., Neufeld, Thomas P., Cabreiro, Filipe, Partridge, Linda
Cyhoeddwyd yn PLoS Genet (2020)

Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease

gan Kerr, Fiona, Sofola-Adesakin, Oyinkan, Ivanov, Dobril K., Gatliff, Jemma, Gomez Perez-Nievas, Beatriz, Bertrand, Hélène C., Martinez, Pedro, Callard, Rebecca, Snoeren, Inge, Cochemé, Helena M., Adcott, Jennifer, Khericha, Mobina, Castillo-Quan, Jorge Iván, Wells, Geoffrey, Noble, Wendy, Thornton, Janet, Partridge, Linda
Cyhoeddwyd yn PLoS Genet (2017)