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Untangling longevity, dauer, and healthspan in Caenorhabditis elegans insulin/IGF-1-signalling
The groundbreaking discovery that lower levels of insulin/IGF-1 signaling (IIS) can induce lifespan extension was reported 24 years ago in the nematode Caenorhabditis elegans. In this organism, mutations in the insulin/IGF-1 receptor gene daf-2 or other genes in this pathway can double lifespan. Sub...
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| 出版年: | Gerontology |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5828946/ https://ncbi.nlm.nih.gov/pubmed/28934747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000480504 |
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