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Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants

Aging research has been very successful at identifying signaling pathways and evolutionarily conserved genes that extend lifespan with the assumption that an increase in lifespan will also increase healthspan. However, it is largely unknown whether we are extending the healthy time of life or simply...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Bansal, Ankita, Zhu, Lihua J., Yen, Kelvin, Tissenbaum, Heidi A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311797/
https://ncbi.nlm.nih.gov/pubmed/25561524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412192112
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