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Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants

Aging research has been very successful at identifying signaling pathways and evolutionarily conserved genes that extend lifespan with the assumption that an increase in lifespan will also increase healthspan. However, it is largely unknown whether we are extending the healthy time of life or simply...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Bansal, Ankita, Zhu, Lihua J., Yen, Kelvin, Tissenbaum, Heidi A.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311797/
https://ncbi.nlm.nih.gov/pubmed/25561524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412192112
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