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Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity
Interventions that delay ageing mobilize mechanisms that protect and repair cellular components(1–3), but it is unknown how these interventions might slow the functional decline of extracellular matrices(4,5), which are also damaged during ageing(6,7). Reduced Insulin/IGF-1 signalling (rIIS) extends...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352135/ https://ncbi.nlm.nih.gov/pubmed/25517099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14021 |
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