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The C. elegans TGF-β Dauer Pathway Regulates Longevity via Insulin Signaling
BACKGROUND: Previous genetic evidence suggested that the C. elegans TGF-β Dauer pathway is responsible solely for regulation of dauer formation, with no role in longevity regulation, while the Insulin/IGF-1 signaling (IIS) pathway regulates both dauer formation and longevity. RESULTS: We have uncove...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3124252/ https://ncbi.nlm.nih.gov/pubmed/17900898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.08.058 |
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