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The C. elegans TGF-β Dauer Pathway Regulates Longevity via Insulin Signaling

BACKGROUND: Previous genetic evidence suggested that the C. elegans TGF-β Dauer pathway is responsible solely for regulation of dauer formation, with no role in longevity regulation, while the Insulin/IGF-1 signaling (IIS) pathway regulates both dauer formation and longevity. RESULTS: We have uncove...

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Bibliografische gegevens
Hoofdauteurs: Shaw, Wendy M., Luo, Shijing, Landis, Jessica, Ashraf, Jasmine, Murphy, Coleen T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124252/
https://ncbi.nlm.nih.gov/pubmed/17900898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.08.058
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