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TGF-β and Insulin Signaling Regulate Reproductive Aging via Oocyte and Germline Quality Maintenance
Reproductive cessation is perhaps the earliest aging phenotypes humans experience. Similarly, C. elegans’ reproduction ceases in mid-adulthood. Although somatic aging has been studied in both worms and humans, mechanisms regulating reproductive aging are not yet understood. Here we show that TGF-β S...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2955983/ https://ncbi.nlm.nih.gov/pubmed/20946987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.09.013 |
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