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TGF-ß Sma/Mab Signaling Mutations Uncouple Reproductive Aging from Somatic Aging

Female reproductive cessation is one of the earliest age-related declines humans experience, occurring in mid-adulthood. Similarly, Caenorhabditis elegans' reproductive span is short relative to its total life span, with reproduction ceasing about a third into its 15–20 day adulthood. All of th...

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Detalhes bibliográficos
Main Authors: Luo, Shijing, Shaw, Wendy M., Ashraf, Jasmine, Murphy, Coleen T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791159/
https://ncbi.nlm.nih.gov/pubmed/20041217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000789
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