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Insulin signaling regulates oocyte quality maintenance with age via Cathepsin B activity
A decline in female reproduction is one of the earliest hallmarks of aging in many animals, including invertebrates and mammals [1–4]. The insulin/insulin-like growth factor-1 signaling (IIS) pathway has a conserved role in regulating longevity [5], and also controls reproductive aging [2,6]. Althou...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Curr Biol |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5893159/ https://ncbi.nlm.nih.gov/pubmed/29478855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2018.01.052 |
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