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The emerging role of autophagic-lysosomal dysfunction in Gaucher disease and Parkinson's disease

Gaucher disease (GD), the commonest lysosomal storage disorder, results from the lack or functional deficiency of glucocerebrosidase (GCase) secondary to mutations in the GBA1 gene. There is an established association between GBA1 mutations and Parkinson's disease (PD), and indeed GBA1 mutation...

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Publicat a:Neural Regen Res
Autors principals: Kinghorn, Kerri J., Asghari, Amir M., Castillo-Quan, Jorge Iván
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications & Media Pvt Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399707/
https://ncbi.nlm.nih.gov/pubmed/28469644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.202934
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