Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis

The quest to extend healthspan via pharmacological means is becoming increasingly urgent, both from a health and economic perspective. Here we show that lithium, a drug approved for human use, promotes longevity and healthspan. We demonstrate that lithium extends lifespan in female and male Drosophi...

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Udgivet i:Cell Rep
Main Authors: Castillo-Quan, Jorge Iván, Li, Li, Kinghorn, Kerri J., Ivanov, Dobril K., Tain, Luke S., Slack, Cathy, Kerr, Fiona, Nespital, Tobias, Thornton, Janet, Hardy, John, Bjedov, Ivana, Partridge, Linda
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850359/
https://ncbi.nlm.nih.gov/pubmed/27068460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.041
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