Suppression of Inflammation with Conditional Deletion of the Prostaglandin E(2) EP2 Receptor in Macrophages and Brain Microglia

Prostaglandin E(2) (PGE(2)), a potent lipid signaling molecule, modulates inflammatory responses through activation of downstream G-protein coupled EP(1–4) receptors. Here, we investigated the cell-specific in vivo function of PGE(2) signaling through its E-prostanoid 2 (EP2) receptor in murine inna...

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Hlavní autoři: Johansson, Jenny U., Pradhan, Suraj, Lokteva, Ludmila A., Woodling, Nathaniel S., Ko, Novie, Brown, Holden D., Wang, Qian, Loh, Christina, Cekanaviciute, Egle, Buckwalter, Marion, Manning-Boğ, Amy B., Andreasson, Katrin I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787507/
https://ncbi.nlm.nih.gov/pubmed/24089506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2203-13.2013
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