Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system

Reduced activity of insulin/insulin-like growth factor signaling (IIS) increases healthy lifespan among diverse animal species. Downstream of IIS, multiple evolutionarily conserved transcription factors (TFs) are required; however, distinct TFs are likely responsible for these effects in different t...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Bolukbasi, Ekin, Woodling, Nathaniel S., Ivanov, Dobril K., Adcott, Jennifer, Foley, Andrea, Rajasingam, Arjunan, Gittings, Lauren M., Aleyakpo, Benjamin, Niccoli, Teresa, Thornton, Janet M., Partridge, Linda
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923679/
https://ncbi.nlm.nih.gov/pubmed/33593901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011491118
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