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Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling
Abstract Background The increasing age of global populations highlights the urgent need to understand the biological underpinnings of ageing. To this end, inhibition of the insulin/insulin-like signalling (IIS) pathway can extend healthy lifespan in diverse animal species, but with trade-offs includ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-09-01
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| Colecção: | BMC Biology |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12915-020-00854-9 |
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