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4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila
Dietary restriction (DR) extends lifespan in multiple species. To examine the mechanisms of lifespan extension upon DR, we assayed genome-wide translational changes in Drosophila. A number of nuclear encoded mitochondrial genes, including those in Complex I and IV of the electron transport chain, sh...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759400/ https://ncbi.nlm.nih.gov/pubmed/19804760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.07.034 |
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