4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila

Dietary restriction (DR) extends lifespan in multiple species. To examine the mechanisms of lifespan extension upon DR, we assayed genome-wide translational changes in Drosophila. A number of nuclear encoded mitochondrial genes, including those in Complex I and IV of the electron transport chain, sh...

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Autors principals: Zid, Brian M., Rogers, Aric, Katewa, Subhash D., Vargas, Miguel A., Kolipinski, Marysia, Lu, Tony Au, Benzer, Seymour, Kapahi, Pankaj
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759400/
https://ncbi.nlm.nih.gov/pubmed/19804760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.07.034
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