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Regulation of Lifespan in Drosophila by Modulation of Genes in the TOR Signaling Pathway

In many species, reducing nutrient intake without causing malnutrition extends lifespan [1-3]. Like DR (dietary restriction), modulation of genes in the insulin-signaling pathway, known to alter nutrient sensing, has been shown to extend lifespan in various species [1-4]. In Drosophila, the target o...

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Detalhes bibliográficos
Main Authors: Kapahi, Pankaj, Zid, Brian M., Harper, Tony, Koslover, Daniel, Sapin, Viveca, Benzer, Seymour
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754830/
https://ncbi.nlm.nih.gov/pubmed/15186745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2004.03.059
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