Intra-myocellular fatty acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster

Changes in fat content have been associated with dietary restriction (DR), but whether they play a causal role in mediating various responses to DR remains unknown. We demonstrate that upon DR, Drosophila melanogaster shift their metabolism towards increasing both fatty acid synthesis and breakdown,...

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Main Authors: Katewa, Subhash D., Demontis, Fabio, Kolipinski, Marysia, Hubbard, Allan, Gill, Matthew S., Perrimon, Norbert, Melov, Simon, Kapahi, Pankaj
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400463/
https://ncbi.nlm.nih.gov/pubmed/22768842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.06.005
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