Induction of Oxidative Stress in Trypanosoma brucei by the Antitrypanosomal Dihydroquinoline OSU-40

Autor He, Shanshan, Dayton, Alex, Kuppusamy, Periannan, Werbovetz, Karl A., Drew, Mark E.
Vydáno 2012

Imidazoles as Potential Anticancer Agents: An Update on Recent Studies

Autor Sharma, Pankaj, LaRosa, Chris, Antwi, Janet, Govindarajan, Rajgopal, Werbovetz, Karl A.
Vydáno v Molecules (2021)

Leishmania tarentolae: Purification and characterization of tubulin and its suitability for antileishmanial drug screening

Autor Yakovich, Adam J., Ragone, Frank L., Alfonzo, Juan D., Sackett, Dan L., Werbovetz, Karl A.
Vydáno 2006

Studies on the Antileishmanial Mechanism of Action of the Arylimidamide DB766: Azole Interactions and Role of CYP5122A1

Autor Pandharkar, Trupti, Zhu, Xiaohua, Mathur, Radhika, Jiang, Jinmai, Schmittgen, Thomas D., Shaha, Chandrima, Werbovetz, Karl A.
Vydáno 2014

Evaluation of Antitrypanosomal Dihydroquinolines for Hepatotoxicity, Mutagenicity, and Methemoglobin Formation In Vitro

Autor Werbovetz, Karl A., Riccio, Edward S., Furimsky, Anna, Richard, Julian V., He, Shanshan, Iyer, Lalitha, Mirsalis, Jon
Vydáno v Int J Toxicol (2014)

Correction for Pandharkar et al., “Studies on the Antileishmanial Mechanism of Action of the Arylimidamide DB766: Azole Interactions and Role of CYP5122A1”

Autor Pandharkar, Trupti, Zhu, Xiaohua, Mathur, Radhika, Jiang, Jinmai, Schmittgen, Thomas D., Shaha, Chandrima, Werbovetz, Karl A.
Vydáno v Antimicrob Agents Chemother (2017)

SAR refinement of antileishmanial N(2),N(4)-disubstituted quinazoline-2,4-diamines

Autor Zhu, Xiaohua, Van Horn, Kurt S., Barber, Megan, Yang, Sihyung, Wang, Michael Zhuo, Manetsch, Roman, Werbovetz, Karl A.
Vydáno v Bioorg Med Chem (2015)

α-Tubulin Mutations Alter Oryzalin Affinity and Microtubule Assembly Properties To Confer Dinitroaniline Resistance

Autor Lyons-Abbott, Sally, Sackett, Dan L., Wloga, Dorota, Gaertig, Jacek, Morgan, Rachel E., Werbovetz, Karl A., Morrissette, Naomi S.
Vydáno 2010

Synthesis and Antiprotozoal Activity of Cationic 1,4-Diphenyl-1H-1,2,3-Triazoles

Autor Bakunov, Stanislav A., Bakunova, Svetlana M., Wenzler, Tanja, Ghebru, Maedot, Werbovetz, Karl A., Brun, Reto, Tidwell, Richard R.
Vydáno 2010

Antileishmanial Activities of Several Classes of Aromatic Dications

Autor Brendle, James J., Outlaw, Abram, Kumar, Arvind, Boykin, David W., Patrick, Donald A., Tidwell, Richard R., Werbovetz, Karl A.
Vydáno 2002

Synthesis and Evaluation of Oryzalin Analogs against Toxoplasma gondii

Autor Endeshaw, Molla M., Li, Catherine, de Leon, Jessica, Yao, Ni, Latibeaudiere, Kirk, Premalatha, Kokku, Morrissette, Naomi, Werbovetz, Karl A.
Vydáno 2010

Antileishmanial Efficacy and Pharmacokinetics of DB766-Azole Combinations

Autor Joice, April C., Yang, Sihyung, Farahat, Abdelbasset A., Meeds, Heidi, Feng, Mei, Li, Junan, Boykin, David W., Wang, Michael Zhuo, Werbovetz, Karl A.
Vydáno v Antimicrob Agents Chemother (2017)

Synthesis, DNA binding and antileishmanial activity of low molecular weight bis-arylimidamides

Autor Banerjee, Moloy, Farahat, Abdelbasset A., Kumar, Arvind, Wenzler, Tanja, Brun, Reto, Munde, Manoj M., Wilson, W. David, Zhu, Xiaohua, Werbovetz, Karl A., Boykin, David W.
Vydáno 2012

Inhibitors of Tubulin Assembly Identified through Screening a Compound Library

Autor Morgan, Rachel E., Ahn, Sunjoo, Nzimiro, Sandra, Fotie, Jean, Phelps, Mitch A., Cotrill, Jeffrey, Yakovich, Adam J., Sackett, Dan L., Dalton, James T., Werbovetz, Karl A.
Vydáno 2008

Synthesis, Biological Evaluation, and Molecular Modeling of 3,5-Substituted-N(1)-phenyl-N(4), N(4)-di-n-butylsulfanilamides as Antikinetoplastid Antimicrotubule Agents

Autor George, Tesmol G., Endeshaw, Molla M., Morgan, Rachel E., Mahasenan, Kiran V., Delfín, Dawn A., Mukherjee, Mitali S., Yakovich, Adam J., Fotie, Jean, Li, Chenglong, Werbovetz, Karl A.
Vydáno 2007

Antileishmanial Activity of a Series of N(2),N(4)-Disubstituted Quinazoline-2,4-diamines

Autor Van Horn, Kurt S., Zhu, Xiaohua, Pandharkar, Trupti, Yang, Sihyung, Vesely, Brian, Vanaerschot, Manu, Dujardin, Jean-Claude, Rijal, Suman, Kyle, Dennis E., Wang, Michael Zhuo, Werbovetz, Karl A., Manetsch, Roman
Vydáno 2014

Antileishmanial and Cytotoxic Activity of Some Highly Oxidized Abietane Diterpenoids from the Bald Cypress, Taxodium distichum

Autor Naman, C. Benjamin, Gromovsky, Anthony D., Vela, Cory M., Fletcher, Joshua N., Gupta, Gaurav, Varikuti, Sanjay, Zhu, Xiaohua, Zywot, Emilia M., Chai, Heebyung, Werbovetz, Karl A., Satoskar, Abhay R., Kinghorn, A. Douglas
Vydáno v J Nat Prod (2016)

Synthesis and pharmacological evaluation of mono-arylimidamides as antileishmanial agents

Autor Zhu, Xiaohua, Farahat, Abdelbasset A., Mattamana, Meena, Joice, April, Pandharkar, Trupti, Holt, Elizabeth, Banerjee, Moloy, Gragg, Jamie L., Hu, Laixing, Kumar, Arvind, Yang, Sihyung, Wang, Michael Zhuo, Boykin, David W., Werbovetz, Karl A.
Vydáno v Bioorg Med Chem Lett (2016)

Novel Arylimidamides for Treatment of Visceral Leishmaniasis

Autor Wang, Michael Zhuo, Zhu, Xiaohua, Srivastava, Anuradha, Liu, Qiang, Sweat, J. Mark, Pandharkar, Trupti, Stephens, Chad E., Riccio, Ed, Parman, Toufan, Munde, Manoj, Mandal, Swati, Madhubala, Rentala, Tidwell, Richard R., Wilson, W. David, Boykin, David W., Hall, James Edwin, Kyle, Dennis E., Werbovetz, Karl A.
Vydáno 2010

Evaluation of Arylimidamides DB1955 and DB1960 as Candidates against Visceral Leishmaniasis and Chagas' Disease: In Vivo Efficacy, Acute Toxicity, Pharmacokinetics, and Toxicology...

Autor Zhu, Xiaohua, Liu, Qiang, Yang, Sihyung, Parman, Toufan, Green, Carol E., Mirsalis, Jon C., de Nazaré Correia Soeiro, Maria, Mello de Souza, Elen, da Silva, Cristiane França, da Gama Jaen Batista, Denise, Stephens, Chad E., Banerjee, Moloy, Farahat, Abdelbasset A., Munde, Manoj, Wilson, W. David, Boykin, David W., Wang, Michael Zhuo, Werbovetz, Karl A.
Vydáno 2012