Synthesis and Antiprotozoal Activity of Cationic 1,4-Diphenyl-1H-1,2,3-Triazoles

Novel dicationic triazoles 1–60 were synthesized by the Pinner method from the corresponding dinitriles, prepared via the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC). The type and the placement of cationic moieties as well as the nature of aromatic substituents influenced in vitro antipro...

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Bibliographische Detailangaben
Hauptverfasser: Bakunov, Stanislav A., Bakunova, Svetlana M., Wenzler, Tanja, Ghebru, Maedot, Werbovetz, Karl A., Brun, Reto, Tidwell, Richard R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113660/
https://ncbi.nlm.nih.gov/pubmed/19928900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901178d
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