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Synthesis and Evaluation of Oryzalin Analogs against Toxoplasma gondii
The synthesis and evaluation of twenty dinitroanilines and related compounds against the obligate intracellular parasite Toxoplasma gondii is reported. Using in vitro cultures of parasites in human fibroblasts, we determined that most of these compounds selectively disrupted Toxoplasma microtubules,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922421/ https://ncbi.nlm.nih.gov/pubmed/20675138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.07.003 |
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