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α-Tubulin Mutations Alter Oryzalin Affinity and Microtubule Assembly Properties To Confer Dinitroaniline Resistance

Plant and protozoan microtubules are selectively sensitive to dinitroanilines, which do not disrupt vertebrate or fungal microtubules. Tetrahymena thermophila is an abundant source of dinitroaniline-sensitive tubulin, and we have modified the single T. thermophila α-tubulin gene to create strains th...

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Autores principales: Lyons-Abbott, Sally, Sackett, Dan L., Wloga, Dorota, Gaertig, Jacek, Morgan, Rachel E., Werbovetz, Karl A., Morrissette, Naomi S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008275/
https://ncbi.nlm.nih.gov/pubmed/20870876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00140-10
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