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Inhibition of Toxoplasma gondii by Indirubin and Tryptanthrin Analogs

New drugs are needed for treatment of Toxoplasma gondii infections. We tested derivatives of principles found in Isatis indigotica for in vitro efficacy against T. gondii infection. Indirubin-3′-oxime analogs showed modest micromolar activity, while tryptanthrin derivatives displayed 50% inhibitory...

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Hlavní autoři: Krivogorsky, Bogdana, Grundt, Peter, Yolken, Robert, Jones-Brando, Lorraine
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592855/
https://ncbi.nlm.nih.gov/pubmed/18824607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00903-08
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