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Inhibition of Toxoplasma gondii by Indirubin and Tryptanthrin Analogs
New drugs are needed for treatment of Toxoplasma gondii infections. We tested derivatives of principles found in Isatis indigotica for in vitro efficacy against T. gondii infection. Indirubin-3′-oxime analogs showed modest micromolar activity, while tryptanthrin derivatives displayed 50% inhibitory...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592855/ https://ncbi.nlm.nih.gov/pubmed/18824607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00903-08 |
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