Novel Arylimidamides for Treatment of Visceral Leishmaniasis

Arylimidamides (AIAs) represent a new class of molecules that exhibit potent antileishmanial activity (50% inhibitory concentration [IC(50)], <1 μM) against both Leishmania donovani axenic amastigotes and intracellular Leishmania, the causative agent for human visceral leishmaniasis (VL). A syste...

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Detalhes bibliográficos
Main Authors: Wang, Michael Zhuo, Zhu, Xiaohua, Srivastava, Anuradha, Liu, Qiang, Sweat, J. Mark, Pandharkar, Trupti, Stephens, Chad E., Riccio, Ed, Parman, Toufan, Munde, Manoj, Mandal, Swati, Madhubala, Rentala, Tidwell, Richard R., Wilson, W. David, Boykin, David W., Hall, James Edwin, Kyle, Dennis E., Werbovetz, Karl A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876428/
https://ncbi.nlm.nih.gov/pubmed/20368397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00250-10
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