Hypercapnia Regulates Gene Expression and Tissue Function

Bằng Shigemura, Masahiko, Welch, Lynn C., Sznajder, Jacob I.
Xuất bản năm Front Physiol (2020)

Carbonic Anhydrase II and Alveolar Fluid Reabsorption during Hypercapnia

Bằng Chen, Jiwang, Lecuona, Emilia, Briva, Arturo, Welch, Lynn C., Sznajder, Jacob I.
Được phát hành 2008

The Hlx homeobox transcription factor is required early in enteric nervous system development

Bằng Bates, Michael D, Dunagan, Dana T, Welch, Lynn C, Kaul, Ajay, Harvey, Richard P
Được phát hành 2006

Salt-inducible kinase 1 is present in lung alveolar epithelial cells and regulates active sodium transport

Bằng Eneling, Kristina, Chen, Jiwang, Welch, Lynn C., Takemori, Hiroshi, Sznajder, Jacob I., Bertorello, Alejandro M.
Được phát hành 2011

Phosphorylation and ubiquitination are necessary for Na,K-ATPase endocytosis during hypoxia

Bằng Dada, Laura A., Welch, Lynn C., Zhou, Guofei, Ben-Saadon, Ronen, Ciechanover, Aaron, Sznajder, Jacob I.
Được phát hành 2007

Extracellular signal-regulated kinase (ERK) participates in the hypercapnia-induced Na,K-ATPase downregulation

Bằng Welch, Lynn C., Lecuona, Emilia, Briva, Arturo, Trejo, Humberto E., Dada, Laura A., Sznajder, Jacob I.
Được phát hành 2010

Cardiac glycosides decrease influenza virus replication by inhibiting cell protein translational machinery

Bằng Amarelle, Luciano, Katzen, Jeremy, Shigemura, Masahiko, Welch, Lynn C., Cajigas, Héctor, Peteranderl, Christin, Celli, Diego, Herold, Susanne, Lecuona, Emilia, Sznajder, Jacob I.
Xuất bản năm Am J Physiol Lung Cell Mol Physiol (2019)

Elevated CO(2) Levels Delay Skeletal Muscle Repair by Increasing Fatty Acid Oxidation

Bằng Ceco, Ermelinda, Celli, Diego, Weinberg, Samuel, Shigemura, Masahiko, Welch, Lynn C., Volpe, Lena, Chandel, Navdeep S., Bharat, Ankit, Lecuona, Emilia, Sznajder, Jacob I.
Xuất bản năm Front Physiol (2021)

Hypercapnia Impairs Lung Neutrophil Function and Increases Mortality in Murine Pseudomonas Pneumonia

Bằng Gates, Khalilah L., Howell, Heather A., Nair, Aisha, Vohwinkel, Christine U., Welch, Lynn C., Beitel, Greg J., Hauser, Alan R., Sznajder, Jacob I., Sporn, Peter H. S.
Được phát hành 2013

Hypoxia Leads to Na,K-ATPase Downregulation via Ca(2+) Release-Activated Ca(2+) Channels and AMPK Activation

Bằng Gusarova, Galina A., Trejo, Humberto E., Dada, Laura A., Briva, Arturo, Welch, Lynn C., Hamanaka, Robert B., Mutlu, Gökhan M., Chandel, Navdeep S., Prakriya, Murali, Sznajder, Jacob I.
Được phát hành 2011

Airborne Particulate Matter Inhibits Alveolar Fluid Reabsorption in Mice via Oxidant Generation

Bằng Mutlu, Gökhan M., Snyder, Colleen, Bellmeyer, Amy, Wang, Helena, Hawkins, Keenan, Soberanes, Saul, Welch, Lynn C., Ghio, Andrew J., Chandel, Navdeep S., Kamp, David, Sznajder, Jacob I., Budinger, G. R. Scott
Được phát hành 2006

Myosin-Va restrains the trafficking of Na(+)/K(+)-ATPase-containing vesicles in alveolar epithelial cells

Bằng Lecuona, Emilia, Minin, Alexander, Trejo, Humberto E., Chen, Jiwang, Comellas, Alejandro P., Sun, Haiying, Grillo, Doris, Nekrasova, Oxana E., Welch, Lynn C., Szleifer, Igal, Gelfand, Vladimir I., Sznajder, Jacob I.
Được phát hành 2009

High CO(2) Levels Impair Alveolar Epithelial Function Independently of pH

Bằng Briva, Arturo, Vadász, István, Lecuona, Emilia, Welch, Lynn C., Chen, Jiwang, Dada, Laura A., Trejo, Humberto E., Dumasius, Vidas, Azzam, Zaher S., Myrianthefs, Pavlos M., Batlle, Daniel, Gruenbaum, Yosef, Sznajder, Jacob I.
Được phát hành 2007

AMP-activated protein kinase regulates CO(2)-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis

Bằng Vadász, István, Dada, Laura A., Briva, Arturo, Trejo, Humberto E., Welch, Lynn C., Chen, Jiwang, Tóth, Péter T., Lecuona, Emilia, Witters, Lee A., Schumacker, Paul T., Chandel, Navdeep S., Seeger, Werner, Sznajder, Jacob I.
Được phát hành 2008

High CO(2) Levels Impair Lung Wound Healing

Bằng Bharat, Ankit, Angulo, Martín, Sun, Haiying, Akbarpour, Mahzad, Alberro, Andrés, Cheng, Yuan, Shigemura, Masahiko, Berdnikovs, Sergejs, Welch, Lynn C., Kanter, Jacob A., Budinger, G. R. Scott, Lecuona, Emilia, Sznajder, Jacob I.
Xuất bản năm Am J Respir Cell Mol Biol (2020)

High CO(2) Levels Cause Skeletal Muscle Atrophy via AMP-activated Kinase (AMPK), FoxO3a Protein, and Muscle-specific Ring Finger Protein 1 (MuRF1)

Bằng Jaitovich, Ariel, Angulo, Martín, Lecuona, Emilia, Dada, Laura A., Welch, Lynn C., Cheng, Yuan, Gusarova, Galina, Ceco, Ermelinda, Liu, Chang, Shigemura, Masahiko, Barreiro, Esther, Patterson, Cam, Nader, Gustavo A., Sznajder, Jacob I.
Xuất bản năm J Biol Chem (2015)

Hypercapnia Suppresses the HIF-dependent Adaptive Response to Hypoxia

Bằng Selfridge, Andrew C., Cavadas, Miguel A. S., Scholz, Carsten C., Campbell, Eric L., Welch, Lynn C., Lecuona, Emilia, Colgan, Sean P., Barrett, Kim E., Sporn, Peter H. S., Sznajder, Jacob I., Cummins, Eoin P., Taylor, Cormac T.
Xuất bản năm J Biol Chem (2016)

Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling

Bằng Shigemura, Masahiko, Lecuona, Emilia, Angulo, Martín, Homma, Tetsuya, Rodríguez, Diego A., Gonzalez-Gonzalez, Francisco J., Welch, Lynn C., Amarelle, Luciano, Kim, Seok-Jo, Kaminski, Naftali, Budinger, G. R. Scott, Solway, Julian, Sznajder, Jacob I.
Xuất bản năm Sci Transl Med (2018)

High CO(2) Leads to Na,K-ATPase Endocytosis via c-Jun Amino-Terminal Kinase-Induced LMO7b Phosphorylation

Bằng Dada, Laura A., Trejo Bittar, Humberto E., Welch, Lynn C., Vagin, Olga, Deiss-Yehiely, Nimrod, Kelly, Aileen M., Baker, Mairead R., Capri, Joseph, Cohn, Whitaker, Whitelegge, Julian P., Vadász, István, Gruenbaum, Yosef, Sznajder, Jacob I.
Xuất bản năm Mol Cell Biol (2015)

Evolutionary Conserved Role of c-Jun-N-Terminal Kinase in CO(2)-Induced Epithelial Dysfunction

Bằng Vadász, István, Dada, Laura A., Briva, Arturo, Helenius, Iiro Taneli, Sharabi, Kfir, Welch, Lynn C., Kelly, Aileen M., Grzesik, Benno A., Budinger, G. R. Scott, Liu, Jing, Seeger, Werner, Beitel, Greg J., Gruenbaum, Yosef, Sznajder, Jacob I.
Được phát hành 2012