Elevated CO(2) Levels Delay Skeletal Muscle Repair by Increasing Fatty Acid Oxidation

Muscle dysfunction often occurs in patients with chronic obstructive pulmonary diseases (COPD) and affects ventilatory and non-ventilatory skeletal muscles. We have previously reported that hypercapnia (elevated CO(2) levels) causes muscle atrophy through the activation of the AMPKα2-FoxO3a-MuRF1 pa...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Ceco, Ermelinda, Celli, Diego, Weinberg, Samuel, Shigemura, Masahiko, Welch, Lynn C., Volpe, Lena, Chandel, Navdeep S., Bharat, Ankit, Lecuona, Emilia, Sznajder, Jacob I.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859333/
https://ncbi.nlm.nih.gov/pubmed/33551852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.630910
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