Elevated CO(2) Levels Cause Mitochondrial Dysfunction and Impair Cell Proliferation

Elevated CO(2) concentrations (hypercapnia) occur in patients with severe lung diseases. Here, we provide evidence that high CO(2) levels decrease O(2) consumption and ATP production and impair cell proliferation independently of acidosis and hypoxia in fibroblasts (N12) and alveolar epithelial cell...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Vohwinkel, Christine U., Lecuona, Emilia, Sun, Haying, Sommer, Natascha, Vadász, István, Chandel, Navdeep S., Sznajder, Jacob I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199454/
https://ncbi.nlm.nih.gov/pubmed/21903582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.290056
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares