Elevated CO(2) Levels Cause Mitochondrial Dysfunction and Impair Cell Proliferation

Elevated CO(2) concentrations (hypercapnia) occur in patients with severe lung diseases. Here, we provide evidence that high CO(2) levels decrease O(2) consumption and ATP production and impair cell proliferation independently of acidosis and hypoxia in fibroblasts (N12) and alveolar epithelial cell...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Vohwinkel, Christine U., Lecuona, Emilia, Sun, Haying, Sommer, Natascha, Vadász, István, Chandel, Navdeep S., Sznajder, Jacob I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199454/
https://ncbi.nlm.nih.gov/pubmed/21903582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.290056
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados