AMP-activated protein kinase regulates CO(2)-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis

Hypercapnia (elevated CO(2) levels) occurs as a consequence of poor alveolar ventilation and impairs alveolar fluid reabsorption (AFR) by promoting Na,K-ATPase endocytosis. We studied the mechanisms regulating CO(2)-induced Na,K-ATPase endocytosis in alveolar epithelial cells (AECs) and alveolar epi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Vadász, István, Dada, Laura A., Briva, Arturo, Trejo, Humberto E., Welch, Lynn C., Chen, Jiwang, Tóth, Péter T., Lecuona, Emilia, Witters, Lee A., Schumacker, Paul T., Chandel, Navdeep S., Seeger, Werner, Sznajder, Jacob I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176184/
https://ncbi.nlm.nih.gov/pubmed/18188452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29723
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares