Phosphorylation and ubiquitination are necessary for Na,K-ATPase endocytosis during hypoxia

As a cellular adaptative response, hypoxia decreases Na,K-ATPase activity by triggering the endocytosis of its α(1) subunit in alveolar epithelial cells. Here, we present evidence that the ubiquitin conjugating system is important in the Na,K-ATPase endocytosis during hypoxia and ubiquitination of N...

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Autores principales: Dada, Laura A., Welch, Lynn C., Zhou, Guofei, Ben-Saadon, Ronen, Ciechanover, Aaron, Sznajder, Jacob I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039720/
https://ncbi.nlm.nih.gov/pubmed/17532187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2007.04.013
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