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Role of Ubiquitination in Na,K-ATPase Regulation during Lung Injury

During acute lung injury edema accumulates in the alveolar space, resulting in hypoxemia due to intrapulmonary shunt. The alveolar Na,K-ATPase, by effecting active Na(+) transport, is essential for removing edema from the alveolar spaces. However, during hypoxia it is endocytosed and degraded, which...

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Detalhes bibliográficos
Main Authors: Helenius, Iiro T., Dada, Laura A., Sznajder, Jacob I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137151/
https://ncbi.nlm.nih.gov/pubmed/20160150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.200907-082JS
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