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Role of Ubiquitination in Na,K-ATPase Regulation during Lung Injury
During acute lung injury edema accumulates in the alveolar space, resulting in hypoxemia due to intrapulmonary shunt. The alveolar Na,K-ATPase, by effecting active Na(+) transport, is essential for removing edema from the alveolar spaces. However, during hypoxia it is endocytosed and degraded, which...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Thoracic Society
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137151/ https://ncbi.nlm.nih.gov/pubmed/20160150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.200907-082JS |
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