Hypercapnia Suppresses the HIF-dependent Adaptive Response to Hypoxia

Molecular oxygen and carbon dioxide are the primary gaseous substrate and product of oxidative metabolism, respectively. Hypoxia (low oxygen) and hypercapnia (high carbon dioxide) are co-incidental features of the tissue microenvironment in a range of pathophysiologic states, including acute and chr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Selfridge, Andrew C., Cavadas, Miguel A. S., Scholz, Carsten C., Campbell, Eric L., Welch, Lynn C., Lecuona, Emilia, Colgan, Sean P., Barrett, Kim E., Sporn, Peter H. S., Sznajder, Jacob I., Cummins, Eoin P., Taylor, Cormac T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882447/
https://ncbi.nlm.nih.gov/pubmed/27044749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.713941
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