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Hypercapnia Suppresses the HIF-dependent Adaptive Response to Hypoxia

Molecular oxygen and carbon dioxide are the primary gaseous substrate and product of oxidative metabolism, respectively. Hypoxia (low oxygen) and hypercapnia (high carbon dioxide) are co-incidental features of the tissue microenvironment in a range of pathophysiologic states, including acute and chr...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Selfridge, Andrew C., Cavadas, Miguel A. S., Scholz, Carsten C., Campbell, Eric L., Welch, Lynn C., Lecuona, Emilia, Colgan, Sean P., Barrett, Kim E., Sporn, Peter H. S., Sznajder, Jacob I., Cummins, Eoin P., Taylor, Cormac T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882447/
https://ncbi.nlm.nih.gov/pubmed/27044749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.713941
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