Hypercapnia Regulates Gene Expression and Tissue Function

מאת Shigemura, Masahiko, Welch, Lynn C., Sznajder, Jacob I.
הוצא לאור ב Front Physiol (2020)

Carbonic Anhydrase II and Alveolar Fluid Reabsorption during Hypercapnia

מאת Chen, Jiwang, Lecuona, Emilia, Briva, Arturo, Welch, Lynn C., Sznajder, Jacob I.
יצא לאור 2008

The Hlx homeobox transcription factor is required early in enteric nervous system development

מאת Bates, Michael D, Dunagan, Dana T, Welch, Lynn C, Kaul, Ajay, Harvey, Richard P
יצא לאור 2006

Salt-inducible kinase 1 is present in lung alveolar epithelial cells and regulates active sodium transport

מאת Eneling, Kristina, Chen, Jiwang, Welch, Lynn C., Takemori, Hiroshi, Sznajder, Jacob I., Bertorello, Alejandro M.
יצא לאור 2011

Phosphorylation and ubiquitination are necessary for Na,K-ATPase endocytosis during hypoxia

מאת Dada, Laura A., Welch, Lynn C., Zhou, Guofei, Ben-Saadon, Ronen, Ciechanover, Aaron, Sznajder, Jacob I.
יצא לאור 2007

Extracellular signal-regulated kinase (ERK) participates in the hypercapnia-induced Na,K-ATPase downregulation

מאת Welch, Lynn C., Lecuona, Emilia, Briva, Arturo, Trejo, Humberto E., Dada, Laura A., Sznajder, Jacob I.
יצא לאור 2010

Cardiac glycosides decrease influenza virus replication by inhibiting cell protein translational machinery

מאת Amarelle, Luciano, Katzen, Jeremy, Shigemura, Masahiko, Welch, Lynn C., Cajigas, Héctor, Peteranderl, Christin, Celli, Diego, Herold, Susanne, Lecuona, Emilia, Sznajder, Jacob I.
הוצא לאור ב Am J Physiol Lung Cell Mol Physiol (2019)

Elevated CO(2) Levels Delay Skeletal Muscle Repair by Increasing Fatty Acid Oxidation

מאת Ceco, Ermelinda, Celli, Diego, Weinberg, Samuel, Shigemura, Masahiko, Welch, Lynn C., Volpe, Lena, Chandel, Navdeep S., Bharat, Ankit, Lecuona, Emilia, Sznajder, Jacob I.
הוצא לאור ב Front Physiol (2021)

Hypercapnia Impairs Lung Neutrophil Function and Increases Mortality in Murine Pseudomonas Pneumonia

מאת Gates, Khalilah L., Howell, Heather A., Nair, Aisha, Vohwinkel, Christine U., Welch, Lynn C., Beitel, Greg J., Hauser, Alan R., Sznajder, Jacob I., Sporn, Peter H. S.
יצא לאור 2013

Hypoxia Leads to Na,K-ATPase Downregulation via Ca(2+) Release-Activated Ca(2+) Channels and AMPK Activation

מאת Gusarova, Galina A., Trejo, Humberto E., Dada, Laura A., Briva, Arturo, Welch, Lynn C., Hamanaka, Robert B., Mutlu, Gökhan M., Chandel, Navdeep S., Prakriya, Murali, Sznajder, Jacob I.
יצא לאור 2011

Airborne Particulate Matter Inhibits Alveolar Fluid Reabsorption in Mice via Oxidant Generation

מאת Mutlu, Gökhan M., Snyder, Colleen, Bellmeyer, Amy, Wang, Helena, Hawkins, Keenan, Soberanes, Saul, Welch, Lynn C., Ghio, Andrew J., Chandel, Navdeep S., Kamp, David, Sznajder, Jacob I., Budinger, G. R. Scott
יצא לאור 2006

Myosin-Va restrains the trafficking of Na(+)/K(+)-ATPase-containing vesicles in alveolar epithelial cells

מאת Lecuona, Emilia, Minin, Alexander, Trejo, Humberto E., Chen, Jiwang, Comellas, Alejandro P., Sun, Haiying, Grillo, Doris, Nekrasova, Oxana E., Welch, Lynn C., Szleifer, Igal, Gelfand, Vladimir I., Sznajder, Jacob I.
יצא לאור 2009

High CO(2) Levels Impair Alveolar Epithelial Function Independently of pH

מאת Briva, Arturo, Vadász, István, Lecuona, Emilia, Welch, Lynn C., Chen, Jiwang, Dada, Laura A., Trejo, Humberto E., Dumasius, Vidas, Azzam, Zaher S., Myrianthefs, Pavlos M., Batlle, Daniel, Gruenbaum, Yosef, Sznajder, Jacob I.
יצא לאור 2007

AMP-activated protein kinase regulates CO(2)-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis

מאת Vadász, István, Dada, Laura A., Briva, Arturo, Trejo, Humberto E., Welch, Lynn C., Chen, Jiwang, Tóth, Péter T., Lecuona, Emilia, Witters, Lee A., Schumacker, Paul T., Chandel, Navdeep S., Seeger, Werner, Sznajder, Jacob I.
יצא לאור 2008

High CO(2) Levels Impair Lung Wound Healing

מאת Bharat, Ankit, Angulo, Martín, Sun, Haiying, Akbarpour, Mahzad, Alberro, Andrés, Cheng, Yuan, Shigemura, Masahiko, Berdnikovs, Sergejs, Welch, Lynn C., Kanter, Jacob A., Budinger, G. R. Scott, Lecuona, Emilia, Sznajder, Jacob I.
הוצא לאור ב Am J Respir Cell Mol Biol (2020)

High CO(2) Levels Cause Skeletal Muscle Atrophy via AMP-activated Kinase (AMPK), FoxO3a Protein, and Muscle-specific Ring Finger Protein 1 (MuRF1)

מאת Jaitovich, Ariel, Angulo, Martín, Lecuona, Emilia, Dada, Laura A., Welch, Lynn C., Cheng, Yuan, Gusarova, Galina, Ceco, Ermelinda, Liu, Chang, Shigemura, Masahiko, Barreiro, Esther, Patterson, Cam, Nader, Gustavo A., Sznajder, Jacob I.
הוצא לאור ב J Biol Chem (2015)

Hypercapnia Suppresses the HIF-dependent Adaptive Response to Hypoxia

מאת Selfridge, Andrew C., Cavadas, Miguel A. S., Scholz, Carsten C., Campbell, Eric L., Welch, Lynn C., Lecuona, Emilia, Colgan, Sean P., Barrett, Kim E., Sporn, Peter H. S., Sznajder, Jacob I., Cummins, Eoin P., Taylor, Cormac T.
הוצא לאור ב J Biol Chem (2016)

Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling

מאת Shigemura, Masahiko, Lecuona, Emilia, Angulo, Martín, Homma, Tetsuya, Rodríguez, Diego A., Gonzalez-Gonzalez, Francisco J., Welch, Lynn C., Amarelle, Luciano, Kim, Seok-Jo, Kaminski, Naftali, Budinger, G. R. Scott, Solway, Julian, Sznajder, Jacob I.
הוצא לאור ב Sci Transl Med (2018)

High CO(2) Leads to Na,K-ATPase Endocytosis via c-Jun Amino-Terminal Kinase-Induced LMO7b Phosphorylation

מאת Dada, Laura A., Trejo Bittar, Humberto E., Welch, Lynn C., Vagin, Olga, Deiss-Yehiely, Nimrod, Kelly, Aileen M., Baker, Mairead R., Capri, Joseph, Cohn, Whitaker, Whitelegge, Julian P., Vadász, István, Gruenbaum, Yosef, Sznajder, Jacob I.
הוצא לאור ב Mol Cell Biol (2015)

Evolutionary Conserved Role of c-Jun-N-Terminal Kinase in CO(2)-Induced Epithelial Dysfunction

מאת Vadász, István, Dada, Laura A., Briva, Arturo, Helenius, Iiro Taneli, Sharabi, Kfir, Welch, Lynn C., Kelly, Aileen M., Grzesik, Benno A., Budinger, G. R. Scott, Liu, Jing, Seeger, Werner, Beitel, Greg J., Gruenbaum, Yosef, Sznajder, Jacob I.
יצא לאור 2012