Targeting SIRPα in cancer

od Ho, Jenny M., Danska, Jayne S., Wang, Jean C.Y.
Wydane 2013

Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice

od Bhatia, Mickie, Wang, Jean C. Y., Kapp, Ursula, Bonnet, Dominique, Dick, John E.
Wydane 1997

Quantitative Analysis Reveals Expansion of Human Hematopoietic Repopulating Cells After Short-term Ex Vivo Culture

od Bhatia, Mickie, Bonnet, Dominique, Kapp, Ursula, Wang, Jean C.Y., Murdoch, Barbara, Dick, John E.
Wydane 1997

CD47-SIRPα Interactions Regulate Macrophage Uptake of Plasmodium falciparum-Infected Erythrocytes and Clearance of Malaria In Vivo

od Ayi, Kodjo, Lu, Ziyue, Serghides, Lena, Ho, Jenny M., Finney, Constance, Wang, Jean C. Y., Liles, W. Conrad, Kain, Kevin C.
Wydane w Infect Immun (2016)

Leukemic stem cell signatures identify novel therapeutics targeting acute myeloid leukemia

od Laverdière, Isabelle, Boileau, Meaghan, Neumann, Andrea L., Frison, Héloïse, Mitchell, Amanda, Ng, Stanley W. K., Wang, Jean C. Y., Minden, Mark D., Eppert, Kolja
Wydane w Blood Cancer J (2018)

SIRPαFc treatment targets human acute myeloid leukemia stem cells

od Galkin, Oleksandr, McLeod, Jessica, Kennedy, James A., Jin, Liqing, Mbong, Nathan, Wong, Mark, Uger, Robert A., Minden, Mark D., Danska, Jayne S., Wang, Jean C.Y.
Wydane w Haematologica (2020)

CD200 expression marks leukemia stem cells in human AML

od Ho, Jenny M., Dobson, Stephanie M., Voisin, Veronique, McLeod, Jessica, Kennedy, James A., Mitchell, Amanda, Jin, Liqing, Eppert, Kolja, Bader, Gary, Minden, Mark D., Dick, John E., Wang, Jean C. Y.
Wydane w Blood Adv (2020)

Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts

od Theocharides, Alexandre P.A., Jin, Liqing, Cheng, Po-Yan, Prasolava, Tatiana K., Malko, Andrei V., Ho, Jenny M., Poeppl, Armando G., van Rooijen, Nico, Minden, Mark D., Danska, Jayne S., Dick, John E., Wang, Jean C.Y.
Wydane 2012

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

od Schenk, Tino, Chen, Weihsu Claire, Göllner, Stefanie, Howell, Louise, Jin, Liqing, Hebestreit, Katja, Klein, Hans-Ulrich, Popescu, Andreea C, Burnett, Alan, Mills, Ken, Casero, Robert A, Marton, Laurence, Woster, Patrick, Minden, Mark D, Dugas, Martin, Wang, Jean C Y, Dick, John E, Müller-Tidow, Carsten, Petrie, Kevin, Zelent, Arthur
Wydane 2012

CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells

od Surka, Christine, Jin, Liqing, Mbong, Nathan, Lu, Chin-Chun, Jang, In Sock, Rychak, Emily, Mendy, Derek, Clayton, Thomas, Tindall, Elizabeth, Hsu, Christy, Fontanillo, Celia, Tran, Eileen, Contreras, Adrian, Ng, Stanley W. K., Matyskiela, Mary, Wang, Kai, Chamberlain, Philip, Cathers, Brian, Carmichael, James, Hansen, Joshua, Wang, Jean C. Y., Minden, Mark D., Fan, Jinhong, Pierce, Daniel W., Pourdehnad, Michael, Rolfe, Mark, Lopez-Girona, Antonia, Dick, John E., Lu, Gang
Wydane w Blood (2021)

INHIBITION OF MITOCHONDRIAL TRANSLATION AS A THERAPEUTIC STRATEGY FOR HUMAN ACUTE MYELOID LEUKEMIA

od Škrtić, Marko, Sriskanthadevan, Shrivani, Jhas, Bozhena, Gebbia, Marinella, Wang, Xiaoming, Wang, Zezhou, Hurren, Rose, Jitkova, Yulia, Gronda, Marcela, Maclean, Neil, Lai, Courteney K., Eberhard, Yanina, Bartoszko, Justyna, Spagnuolo, Paul, Rutledge, Angela C., Datti, Alessandro, Ketela, Troy, Moffat, Jason, Robinson, Brian H., Cameron, Jessie H., Wrana, Jeffery, Eaves, Connie J., Minden, Mark D., Wang, Jean C.Y., Dick, John E., Humphries, Keith, Nislow, Corey, Giaever, Guri, Schimmer, Aaron D.
Wydane 2011

Identification of pre-leukemic hematopoietic stem cells in acute leukemia

od Shlush, Liran I., Zandi, Sasan, Mitchell, Amanda, Chen, Weihsu Claire, Brandwein, Joseph M., Gupta, Vikas, Kennedy, James A., Schimmer, Aaron D., Schuh, Andre C., Yee, Karen W., McLeod, Jessica L., Doedens, Monica, Medeiros, Jessie J.F., Marke, Rene, Kim, Hyeoung Joon, Lee, Kwon, McPherson, John D., Hudson, Thomas J., Brown, Andrew M.K., Trinh, Quang M., Stein, Lincoln D., Minden, Mark D., Wang, Jean C.Y., Dick, John E.
Wydane w Nature (2014)

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

od Lechman, Eric R., Gentner, Bernhard, Ng, Stanley W.K., Schoof, Erwin M., van Galen, Peter, Kennedy, James A., Nucera, Silvia, Ciceri, Fabio, Kaufmann, Kerstin B., Takayama, Naoya, Dobson, Stephanie M., Trotman-Grant, Aaron, Krivdova, Gabriela, Elzinga, Janneke, Mitchell, Amanda, Nilsson, Björn, Hermans, Karin G., Eppert, Kolja, Marke, Rene, Isserlin, Ruth, Voisin, Veronique, Bader, Gary D., Zandstra, Peter W., Golub, Todd R., Ebert, Benjamin L., Lu, Jun, Minden, Mark, Wang, Jean C.Y., Naldini, Luigi, Dick, John E.
Wydane w Cancer Cell (2016)

Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells

od Nieborowska-Skorska, Margaret, Sullivan, Katherine, Dasgupta, Yashodhara, Podszywalow-Bartnicka, Paulina, Hoser, Grazyna, Maifrede, Silvia, Martinez, Esteban, Di Marcantonio, Daniela, Bolton-Gillespie, Elisabeth, Cramer-Morales, Kimberly, Lee, Jaewong, Li, Min, Slupianek, Artur, Gritsyuk, Daniel, Cerny-Reiterer, Sabine, Seferynska, Ilona, Stoklosa, Tomasz, Bullinger, Lars, Zhao, Huaqing, Gorbunova, Vera, Piwocka, Katarzyna, Valent, Peter, Civin, Curt I., Muschen, Markus, Dick, John E., Wang, Jean C.Y., Bhatia, Smita, Bhatia, Ravi, Eppert, Kolja, Minden, Mark D., Sykes, Stephen M., Skorski, Tomasz
Wydane w J Clin Invest (2017)

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

od Lechman, Eric R., Gentner, Bernhard, Ng, Stanley W.K., Schoof, Erwin M., van Galen, Peter, Kennedy, James A., Nucera, Silvia, Ciceri, Fabio, Kaufmann, Kerstin B., Takayama, Naoya, Dobson, Stephanie M., Trotman-Grant, Aaron, Krivdova, Gabriela, Elzinga, Janneke, Mitchell, Amanda, Nilsson, Björn, Hermans, Karin G., Eppert, Kolja, Marke, Rene, Isserlin, Ruth, Voisin, Veronique, Bader, Gary D., Zandstra, Peter W., Golub, Todd R., Ebert, Benjamin L., Lu, Jun, Minden, Mark, Wang, Jean C.Y., Naldini, Luigi, Dick, John E.
Wydane w Cancer Cell (2016)

Sphingosine-1-Phosphate Receptor 3 Potentiates Inflammatory Programs in Normal and Leukemia Stem Cells to Promote Differentiation

od Xie, Stephanie Z., Kaufmann, Kerstin B., Wang, Weijia, Chan-Seng-Yue, Michelle, Gan, Olga I., Laurenti, Elisa, Garcia-Prat, Laura, Takayanagi, Shin-ichiro, Ng, Stanley W.K., Xu, ChangJiang, Zeng, Andy G.X., Jin, Liqing, McLeod, Jessica, Wagenblast, Elvin, Mitchell, Amanda, Kennedy, James A., Liu, Qiang, Boutzen, Héléna, Kleinau, Melissa, Jargstorf, Joseph, Holmes, Gareth, Zhang, Yang, Voisin, Veronique, Bader, Gary D., Wang, Jean C.Y., Hannun, Yusuf A., Luberto, Chiara, Schroeder, Timm, Minden, Mark D., Dick, John E.
Wydane w Blood Cancer Discov (2020)

Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors

od Sukhai, Mahadeo A., Prabha, Swayam, Hurren, Rose, Rutledge, Angela C., Lee, Anna Y., Sriskanthadevan, Shrivani, Sun, Hong, Wang, Xiaoming, Skrtic, Marko, Seneviratne, Ayesh, Cusimano, Maria, Jhas, Bozhena, Gronda, Marcela, MacLean, Neil, Cho, Eunice E., Spagnuolo, Paul A., Sharmeen, Sumaiya, Gebbia, Marinella, Urbanus, Malene, Eppert, Kolja, Dissanayake, Dilan, Jonet, Alexia, Dassonville-Klimpt, Alexandra, Li, Xiaoming, Datti, Alessandro, Ohashi, Pamela S., Wrana, Jeff, Rogers, Ian, Sonnet, Pascal, Ellis, William Y., Corey, Seth J., Eaves, Connie, Minden, Mark D., Wang, Jean C.Y., Dick, John E., Nislow, Corey, Giaever, Guri, Schimmer, Aaron D.
Wydane 2012

Inhibition of the mitochondrial protease, ClpP, as a therapeutic strategy for human acute myeloid leuekmia

od Cole, Alicia, Wang, Zezhou, Coyaud, Etienne, Voisin, Veronique, Gronda, Marcela, Jitkova, Yulia, Mattson, Rachel, Hurren, Rose, Babovic, Sonja, Maclean, Neil, Restall, Ian, Wang, Xiaoming, Jeyaraju, Danny V., Sukhai, Mahadeo A., Prabha, Swayam, Bashir, Shaheena, Ramakrishnan, Ashwin, Leung, Elisa, Qia, Yi Hua, Zhang, Nianxian, Combes, Kevin R., Ketela, Troy, Lin, Fengshu, Houry, Walid A., Aman, Ahmed, Al-awar, Rima, Zheng, Wei, Wienholds, Erno, Xu, Chang Jiang, Dick, John, Wang, Jean C.Y., Moffat, Jason, Minden, Mark D., Eaves, Connie J., Bader, Gary D., Hao, Zhenyue, Kornblau, Steven M., Raught, Brian, Schimmer, Aaron D.
Wydane w Cancer Cell (2015)

Prediction of acute myeloid leukaemia risk in healthy individuals

od Abelson, Sagi, Collord, Grace, Ng, Stanley W.K., Weissbrod, Omer, Cohen, Netta Mendelson, Niemeyer, Elisabeth, Barda, Noam, Zuzarte, Philip C., Heisler, Lawrence, Sundaravadanam, Yogi, Luben, Robert, Hayat, Shabina, Wang, Ting Ting, Zhao, Zhen, Cirlan, Iulia, Pugh, Trevor J., Soave, David, Ng, Karen, Latimer, Calli, Hardy, Claire, Raine, Keiran, Jones, David, Hoult, Diana, Britten, Abigail, McPherson, John D., Johansson, Mattias, Mbabaali, Faridah, Eagles, Jenna, Miller, Jessica, Pasternack, Danielle, Timms, Lee, Krzyzanowski, Paul, Awadalla, Phillip, Costa, Rui, Segal, Eran, Bratman, Scott V., Beer, Philip, Behjati, Sam, Martincorena, Inigo, Wang, Jean C.Y., Bowles, Kristian M., Quirós, J Ramón, Karakatsani, Anna, La Vecchia, Carlo, Trichopoulou, Antonia, Salamanca-Fernández, Elena, Huerta, José M., Barricarte, Aurelio, Travis, Ruth C., Tumino, Rosario, Masala, Giovanna, Boeing, Heiner, Panico, Salvatore, Kaaks, Rudolf, Krämer, Alwin, Sieri, Sabina, Riboli, Elio, Vineis, Paolo, Foll, Matthieu, McKay, James, Polidoro, Silvia, Sala, Núria, Khaw, Kay-Tee, Vermeulen, Roel, Campbell, Peter J, Papaemmanuil, Elli, Minden, Mark D, Tanay, Amos, Balicer, Ran D, Wareham, Nicholas J, Gerstung, Moritz, Dick, John E., Brennan, Paul, Vassiliou, George S., Shlush, Liran I.
Wydane w Nature (2018)