Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts

Although tumor surveillance by T and B lymphocytes is well studied, the role of innate immune cells, in particular macrophages, is less clear. Moreover, the existence of subclonal genetic and functional diversity in some human cancers such as leukemia underscores the importance of defining tumor sur...

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Detalhes bibliográficos
Main Authors: Theocharides, Alexandre P.A., Jin, Liqing, Cheng, Po-Yan, Prasolava, Tatiana K., Malko, Andrei V., Ho, Jenny M., Poeppl, Armando G., van Rooijen, Nico, Minden, Mark D., Danska, Jayne S., Dick, John E., Wang, Jean C.Y.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457732/
https://ncbi.nlm.nih.gov/pubmed/22945919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120502
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