Role for CD47-SIRPα signaling in xenograft rejection by macrophages

We have previously proven that human macrophages can phagocytose porcine cells even in the absence of Ab or complement opsonization, indicating that macrophages present a pivotal immunological obstacle to xenotransplantation. A recent report indicates that the signal regulatory protein (SIRP)α is a...

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Detalhes bibliográficos
Main Authors: Ide, Kentaro, Wang, Hui, Tahara, Hiroyuki, Liu, Jianxiang, Wang, Xiaoying, Asahara, Toshimasa, Sykes, Megan, Yang, Yong-Guang, Ohdan, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829264/
https://ncbi.nlm.nih.gov/pubmed/17360380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609661104
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