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Role for CD47-SIRPα signaling in xenograft rejection by macrophages
We have previously proven that human macrophages can phagocytose porcine cells even in the absence of Ab or complement opsonization, indicating that macrophages present a pivotal immunological obstacle to xenotransplantation. A recent report indicates that the signal regulatory protein (SIRP)α is a...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1829264/ https://ncbi.nlm.nih.gov/pubmed/17360380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609661104 |
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