Role for CD47-SIRPα signaling in xenograft rejection by macrophages

We have previously proven that human macrophages can phagocytose porcine cells even in the absence of Ab or complement opsonization, indicating that macrophages present a pivotal immunological obstacle to xenotransplantation. A recent report indicates that the signal regulatory protein (SIRP)α is a...

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Bibliografiska uppgifter
Huvudupphovsmän: Ide, Kentaro, Wang, Hui, Tahara, Hiroyuki, Liu, Jianxiang, Wang, Xiaoying, Asahara, Toshimasa, Sykes, Megan, Yang, Yong-Guang, Ohdan, Hideki
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2007
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829264/
https://ncbi.nlm.nih.gov/pubmed/17360380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609661104
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