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Role for CD47-SIRPα signaling in xenograft rejection by macrophages

We have previously proven that human macrophages can phagocytose porcine cells even in the absence of Ab or complement opsonization, indicating that macrophages present a pivotal immunological obstacle to xenotransplantation. A recent report indicates that the signal regulatory protein (SIRP)α is a...

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Bibliografske podrobnosti
Main Authors: Ide, Kentaro, Wang, Hui, Tahara, Hiroyuki, Liu, Jianxiang, Wang, Xiaoying, Asahara, Toshimasa, Sykes, Megan, Yang, Yong-Guang, Ohdan, Hideki
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829264/
https://ncbi.nlm.nih.gov/pubmed/17360380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609661104
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