Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts

Although tumor surveillance by T and B lymphocytes is well studied, the role of innate immune cells, in particular macrophages, is less clear. Moreover, the existence of subclonal genetic and functional diversity in some human cancers such as leukemia underscores the importance of defining tumor sur...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Theocharides, Alexandre P.A., Jin, Liqing, Cheng, Po-Yan, Prasolava, Tatiana K., Malko, Andrei V., Ho, Jenny M., Poeppl, Armando G., van Rooijen, Nico, Minden, Mark D., Danska, Jayne S., Dick, John E., Wang, Jean C.Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457732/
https://ncbi.nlm.nih.gov/pubmed/22945919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120502
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