PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas

von Czyż, Małgorzata, Toma, Monika, Gajos-Michniewicz, Anna, Majchrzak, Kinga, Hoser, Grazyna, Szemraj, Janusz, Nieborowska-Skorska, Margaret, Cheng, Phil, Gritsyuk, Daniel, Levesque, Mitchell, Dummer, Reinhard, Sliwinski, Tomasz, Skorski, Tomasz
Veröffentlicht in Oncotarget (2016)

IGH/MYC Translocation Associates with BRCA2 Deficiency and Synthetic Lethality to PARP1 Inhibitors

von Maifrede, Silvia, Martin, Kayla A., Podszywalow-Bartnicka, Paulina, Sullivan, Katherine, Langer, Samantha K., Nejati, Reza, Dasgupta, Yashodhara, Hulse, Michael, Gritsyuk, Daniel, Nieborowska-Skorska, Margaret, Lupey-Green, Lena N., Zhao, Huaqing, Piwocka, Katarzyna, Wasik, Mariusz, Tempera, Italo, Skorski, Tomasz
Veröffentlicht in Mol Cancer Res (2017)

Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells

von Nieborowska-Skorska, Margaret, Sullivan, Katherine, Dasgupta, Yashodhara, Podszywalow-Bartnicka, Paulina, Hoser, Grazyna, Maifrede, Silvia, Martinez, Esteban, Di Marcantonio, Daniela, Bolton-Gillespie, Elisabeth, Cramer-Morales, Kimberly, Lee, Jaewong, Li, Min, Slupianek, Artur, Gritsyuk, Daniel, Cerny-Reiterer, Sabine, Seferynska, Ilona, Stoklosa, Tomasz, Bullinger, Lars, Zhao, Huaqing, Gorbunova, Vera, Piwocka, Katarzyna, Valent, Peter, Civin, Curt I., Muschen, Markus, Dick, John E., Wang, Jean C.Y., Bhatia, Smita, Bhatia, Ravi, Eppert, Kolja, Minden, Mark D., Sykes, Stephen M., Skorski, Tomasz
Veröffentlicht in J Clin Invest (2017)